Evaluation of the Immunological Efficacy of an LNP-mRNA Vaccine Prepared from Varicella Zoster Virus Glycoprotein gE with a Double-Mutated Carboxyl Terminus in Different Untranslated Regions in Mice

Cell-mediated immunity (CMI) plays a key role in the effectiveness of varicella zoster virus (VZV) vaccines, and mRNA vaccines have an innate advantage in inducing CMI. Glycoprotein E (gE) has been used widely as an antigen for VZV vaccines, and carboxyl-terminal mutations of gE are associated with...

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Detalles Bibliográficos
Autores principales: Wang, Yunfei, Cao, Han, Lin, Kangyang, Hu, Jingping, Luan, Ning, Liu, Cunbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534744/
https://www.ncbi.nlm.nih.gov/pubmed/37766151
http://dx.doi.org/10.3390/vaccines11091475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534744/
https://www.ncbi.nlm.nih.gov/pubmed/37766151
http://dx.doi.org/10.3390/vaccines11091475

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