Group A Streptococcus Vaccine Targeting the Erythrogenic Toxins SpeA and SpeB Is Safe and Immunogenic in Rabbits and Does Not Induce Antibodies Associated with Autoimmunity

Group A streptococcus (GAS) is a global pathogen associated with significant morbidity and mortality for which there is currently no licensed vaccine. Vaccine development has been slow, mostly due to safety concerns regarding streptococcal antigens associated with autoimmunity and related complicati...

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Detalles Bibliográficos
Autores principales: Troese, Matthew J., Burlet, Elodie, Cunningham, Madeleine W., Alvarez, Kathy, Bentley, Rebecca, Thomas, Nissy, Carwell, Shanna, Morefield, Garry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534881/
https://www.ncbi.nlm.nih.gov/pubmed/37766180
http://dx.doi.org/10.3390/vaccines11091504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534881/
https://www.ncbi.nlm.nih.gov/pubmed/37766180
http://dx.doi.org/10.3390/vaccines11091504

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