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Group A Streptococcus Vaccine Targeting the Erythrogenic Toxins SpeA and SpeB Is Safe and Immunogenic in Rabbits and Does Not Induce Antibodies Associated with Autoimmunity
Group A streptococcus (GAS) is a global pathogen associated with significant morbidity and mortality for which there is currently no licensed vaccine. Vaccine development has been slow, mostly due to safety concerns regarding streptococcal antigens associated with autoimmunity and related complicati...
Autores principales: | Troese, Matthew J., Burlet, Elodie, Cunningham, Madeleine W., Alvarez, Kathy, Bentley, Rebecca, Thomas, Nissy, Carwell, Shanna, Morefield, Garry L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534881/ https://www.ncbi.nlm.nih.gov/pubmed/37766180 http://dx.doi.org/10.3390/vaccines11091504 |
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