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Biomedical engineering approaches for the delivery of JAGGED1 as a potential tissue regenerative therapy

JAG1 is a ligand that activates the NOTCH signaling pathway which plays a crucial role in determining cell fate behavior through cell-to-cell signaling. JAG1-NOTCH signaling is required for mesenchymal stem cell (MSC) differentiation into cardiomyocytes and cranial neural crest (CNC) cells different...

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Detalles Bibliográficos
Autores principales: Kaimari, Sundus, Kamalakar, Archana, Goudy, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534981/
https://www.ncbi.nlm.nih.gov/pubmed/37781534
http://dx.doi.org/10.3389/fbioe.2023.1217211