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Liquid Chromatography Methods for Analysis of mRNA Poly(A) Tail Length and Heterogeneity

[Image: see text] Messenger RNA (mRNA) is a new class of therapeutic compounds. The current advances in mRNA technology require the development of efficient analytical methods. In this work, we describe the development of several methods for measurement of mRNA poly(A) tail length and heterogeneity....

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Detalles Bibliográficos
Autores principales: Gilar, Martin, Doneanu, Catalin, Gaye, Maissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535021/
https://www.ncbi.nlm.nih.gov/pubmed/37696042
http://dx.doi.org/10.1021/acs.analchem.3c02552