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Enfortumab vedotin in metastatic urothelial carcinoma: the solution EVentually?

Metastatic urothelial carcinoma (mUC) is an aggressive malignancy with a dismal prognosis. Enfortumab vedotin (EV) is an antibody-drug conjugate consisting of an antibody targeting Nectin-4. This protein is highly expressed in UC cells. After binding, monomethyl auristatin E is released into cells,...

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Detalles Bibliográficos
Autores principales: Maiorano, Brigida Anna, Catalano, Martina, Maiello, Evaristo, Roviello, Giandomenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535083/
https://www.ncbi.nlm.nih.gov/pubmed/37781180
http://dx.doi.org/10.3389/fonc.2023.1254906