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Single-cell analysis of graft-infiltrating host cells identifies caspase-1 as a potential therapeutic target for heart transplant rejection

AIMS: Understanding the cellular mechanisms underlying early allograft rejection is crucial for the development of effective immunosuppressant strategies. This study aims to investigate the cellular composition of graft-infiltrating cells during the early rejection stage at a single-cell level and i...

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Detalles Bibliográficos
Autores principales: Wu, Zhichao, Liang, Jialiang, Zhu, Shuoji, Liu, Nanbo, Zhao, Mingyi, Xiao, Fei, Li, Guanhua, Yu, Changjiang, Jin, Chengyu, Ma, Jinshan, Sun, Tucheng, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535112/
https://www.ncbi.nlm.nih.gov/pubmed/37781362
http://dx.doi.org/10.3389/fimmu.2023.1251028