Cargando…

Single-cell analysis of graft-infiltrating host cells identifies caspase-1 as a potential therapeutic target for heart transplant rejection

AIMS: Understanding the cellular mechanisms underlying early allograft rejection is crucial for the development of effective immunosuppressant strategies. This study aims to investigate the cellular composition of graft-infiltrating cells during the early rejection stage at a single-cell level and i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Zhichao, Liang, Jialiang, Zhu, Shuoji, Liu, Nanbo, Zhao, Mingyi, Xiao, Fei, Li, Guanhua, Yu, Changjiang, Jin, Chengyu, Ma, Jinshan, Sun, Tucheng, Zhu, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535112/ https://www.ncbi.nlm.nih.gov/pubmed/37781362 http://dx.doi.org/10.3389/fimmu.2023.1251028

Ejemplares similares

Injectable conductive gelatin methacrylate / oxidized dextran hydrogel encapsulating umbilical cord mesenchymal stem cells for myocardial infarction treatment
por: Zhu, Shuoji, et al.
Publicado: (2021)

Construction of multifunctional hydrogel with metal-polyphenol capsules for infected full-thickness skin wound healing
por: Liu, Nanbo, et al.
Publicado: (2022)

Graft-infiltrating host dendritic cells play a key role in organ transplant rejection
por: Zhuang, Quan, et al.
Publicado: (2016)

Maturation of induced pluripotent stem cell-derived cardiomyocytes and its therapeutic effect on myocardial infarction in mouse
por: Wu, Peng, et al.
Publicado: (2022)

Histopathological analysis of infiltrating T cell subsets in acute T cell-mediated rejection in the kidney transplant
por: Salcido-Ochoa, Francisco, et al.
Publicado: (2017)

Cells mediating graft rejection in the mouse. I. Lyt-1 cells mediate skin graft rejection
Publicado: (1981)

Diagnostic Biomarkers and Immune Infiltration in Patients With T Cell-Mediated Rejection After Kidney Transplantation
por: Zhou, Hai, et al.
Publicado: (2022)

Impaired Function of Peripherally Induced Regulatory T Cells in Hosts at High Risk of Graft Rejection
por: Inomata, Takenori, et al.
Publicado: (2016)

Potential correlation of allograft infiltrating group 2 innate lymphoid cells with acute rejection after liver transplantation
por: Sun, Jie, et al.
Publicado: (2022)

Infiltrating cells from host brain restore the microglial population in grafted cortical tissue
por: Wang, Cong, et al.
Publicado: (2016)

Graft rejection markers in children undergoing hematopoietic cell transplant for bone marrow failure
por: Sabulski, Anthony, et al.
Publicado: (2021)

Extracellular Vesicles as Bridges Between Host Immune Cells and Graft Organ During Cellular Rejection
por: Barile, Lucio
Publicado: (2023)

Caspase-11 signaling enhances graft-versus-host disease
por: Lu, Yanyan, et al.
Publicado: (2019)

Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection
por: Asano, Yuta, et al.
Publicado: (2021)

An MMP-degradable and conductive hydrogel to stabilize HIF-1α for recovering cardiac functions
por: Wei, Xiaojuan, et al.
Publicado: (2022)

Cardiovascular Disease and Exercise: From Molecular Mechanisms to Clinical Applications
por: Wang, Bo, et al.
Publicado: (2022)

Retraction: Wang et al. Cardiovascular Disease and Exercise: From Molecular Mechanisms to Clinical Applications. J. Clin. Med. 2022, 11, 7511
por: Wang, Bo, et al.
Publicado: (2023)

Dual Role of Natural Killer Cells on Graft Rejection and Control of Cytomegalovirus Infection in Renal Transplantation
por: López-Botet, Miguel, et al.
Publicado: (2017)

The impact of Host vs. Graft mismatches on rejection of haploidentical bone marrow transplants in thalassemia patients using posttransplant cyclophosphamide
por: Marwah, Priya, et al.
Publicado: (2019)

Infiltration of Macrophages Correlates with Severity of Allograft Rejection and Outcome in Human Kidney Transplantation
por: Bergler, Tobias, et al.
Publicado: (2016)

Profiling the Resident and Infiltrating Monocyte/Macrophages during Rejection following Kidney Transplantation
por: Wang, Jie, et al.
Publicado: (2020)

Characteristic Genes and Immune Infiltration Analysis for Acute Rejection after Kidney Transplantation
por: Lu, Zechao, et al.
Publicado: (2022)

Immune Cell Infiltrate in Chronic-Active Antibody-Mediated Rejection
por: Sablik, Kasia A., et al.
Publicado: (2020)

The impact of early and late acute rejection on graft survival in renal transplantation
por: Koo, Eun Hee, et al.
Publicado: (2015)

Does the timing of acute rejection matter with the graft outcome in kidney transplantation?
por: Kim, Myung-Gyu
Publicado: (2015)

Imaging indications and findings in evaluation of lung transplant graft dysfunction and rejection
por: Bin Saeedan, Mnahi, et al.
Publicado: (2020)

Graft dysfunction and rejection of lung transplant, a review on diagnosis and management
por: Sun, Haishuang, et al.
Publicado: (2022)

Human A2-CAR T cells reject HLA-A2+ human islets transplanted into mice without inducing graft versus host disease
por: Ellis, Cara E., et al.
Publicado: (2023)

Local immune cell infiltration in cutaneous acute graft versus host disease
por: Sennett, Rachel, et al.
Publicado: (2020)

Heterogeneity in allospecific T cell function in transplant-tolerant hosts determines susceptibility to rejection following infection
por: McIntosh, Christine M., et al.
Publicado: (2023)

Graft rejection in component keratoplasty
por: Deshmukh, Rashmi, et al.
Publicado: (2023)

Immunopathogenesis of corneal graft rejection
por: Maharana, Prafulla Kumar, et al.
Publicado: (2023)

The Effect of Histological CD20-Positive B Cell Infiltration in Acute Cellular Rejection on Kidney Transplant Allograft Survival
por: Jiang, Yan, et al.
Publicado: (2016)

Screening and identification of key regulatory connections and immune cell infiltration characteristics for lung transplant rejection using mucosal biopsies
por: Xiu, Meng-xi, et al.
Publicado: (2020)

Treatment With Melatonin After Corneal Graft Attenuates Rejection
por: Zhu, Ziqian, et al.
Publicado: (2021)

Reduced PARP1 as a Serum Biomarker for Graft Rejection in Kidney Transplantation
por: Srivastava, Meera, et al.
Publicado: (2015)

A Comprehensive Review on Schisandrin B and Its Biological Properties
por: Nasser, M. I., et al.
Publicado: (2020)

Author Correction: Caspase-11 signaling enhances graft-versus-host disease
por: Lu, Yanyan, et al.
Publicado: (2020)

Screening Genes Promoting Exit from Naive Pluripotency Based on Genome-Scale CRISPR-Cas9 Knockout
por: Yang, Bin, et al.
Publicado: (2020)

Myeloid-Derived Suppressor Cells Participate in Preventing Graft Rejection
por: Wang, Yan, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_370ibvcjk7u2dchabeb32fh0u9