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Modulation of Human Dendritic Cell Functions by Phosphodiesterase-4 Inhibitors: Potential Relevance for the Treatment of Respiratory Diseases

Inhibitors of phosphodiesterase-4 (PDE4) are small-molecule drugs that, by increasing the intracellular levels of cAMP in immune cells, elicit a broad spectrum of anti-inflammatory effects. As such, PDE4 inhibitors are actively studied as therapeutic options in a variety of human diseases characteri...

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Detalles Bibliográficos
Autores principales: Nguyen, Hoang Oanh, Tiberio, Laura, Facchinetti, Fabrizio, Ripari, Giulia, Violi, Valentina, Villetti, Gino, Salvi, Valentina, Bosisio, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535230/
https://www.ncbi.nlm.nih.gov/pubmed/37765223
http://dx.doi.org/10.3390/pharmaceutics15092254