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Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation

Currently, the treatment of Proteus mirabilis infections is considered to be complicated as the organism has become resistant to numerous antibiotic classes. Therefore, new inhibitors should be developed, targeting bacterial molecular functions. Methionine tRNA synthetase (MetRS), a member of the am...

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Detalles Bibliográficos
Autores principales: Elbaramawi, Samar S., Eissa, Ahmed G., Noureldin, Nada A., Simons, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535265/
https://www.ncbi.nlm.nih.gov/pubmed/37765071
http://dx.doi.org/10.3390/ph16091263