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Preparation of Dihydromyricetin-Loaded Self-Emulsifying Drug Delivery System and Its Anti-Alcoholism Effect

Intraperitoneal injection of dihydromyricetin (DMY) has shown promising potential in the treatment of alcoholism. However, its therapeutic effect is limited due to its low solubility, poor stability, and high gut-liver first-pass metabolism, resulting in very low oral bioavailability. In this study,...

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Detalles Bibliográficos
Autores principales: Dong, Jianxia, Wang, Shu, Mao, Jiamin, Wang, Zhidan, Zhao, Shiying, Ren, Qiao, Kang, Jialing, Ye, Jing, Xu, Xiaohong, Zhu, Yujin, Zhang, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535266/
https://www.ncbi.nlm.nih.gov/pubmed/37765265
http://dx.doi.org/10.3390/pharmaceutics15092296