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Benzimidazole-Based Schiff Base Hybrid Scaffolds: A Promising Approach to Develop Multi-Target Drugs for Alzheimer’s Disease

A series of benzimidazole-based Schiff base derivatives (1–18) were synthesized and structurally elucidated through (1)H NMR, (13)C NMR and HREI-MS analysis. Subsequently, these synthetic derivatives were subjected to evaluation for their inhibitory capabilities against acetylcholinesterase (AChE) a...

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Detalles Bibliográficos
Autores principales: Hussain, Rafaqat, Khan, Shoaib, Ullah, Hayat, Ali, Farhan, Khan, Yousaf, Sardar, Asma, Iqbal, Rashid, Ataya, Farid S., El-Sabbagh, Nasser M., Batiha, Gaber El-Saber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535318/
https://www.ncbi.nlm.nih.gov/pubmed/37765088
http://dx.doi.org/10.3390/ph16091278