Enhanced IL-17 Producing and Maintained Cytolytic Effector Functions of Gut Mucosal CD161(+)CD8(+) T Cells in SIV-Infected Rhesus Macaques

Previous studies have indicated that the loss of CD161-expressing CD4(+) Th17 cells is linked to the progression of chronic HIV. These cells are significantly depleted in peripheral blood and gut mucosa of HIV-infected individuals, contributing to inflammation and disruption of the gut barrier. Howe...

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Detalles Bibliográficos
Autores principales: Thirugnanam, Siva, Walker, Edith M., Schiro, Faith, Aye, Pyone P., Rappaport, Jay, Rout, Namita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535321/
https://www.ncbi.nlm.nih.gov/pubmed/37766350
http://dx.doi.org/10.3390/v15091944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535321/
https://www.ncbi.nlm.nih.gov/pubmed/37766350
http://dx.doi.org/10.3390/v15091944

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