Cargando…

Enhanced IL-17 Producing and Maintained Cytolytic Effector Functions of Gut Mucosal CD161(+)CD8(+) T Cells in SIV-Infected Rhesus Macaques

Previous studies have indicated that the loss of CD161-expressing CD4(+) Th17 cells is linked to the progression of chronic HIV. These cells are significantly depleted in peripheral blood and gut mucosa of HIV-infected individuals, contributing to inflammation and disruption of the gut barrier. Howe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thirugnanam, Siva, Walker, Edith M., Schiro, Faith, Aye, Pyone P., Rappaport, Jay, Rout, Namita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535321/ https://www.ncbi.nlm.nih.gov/pubmed/37766350 http://dx.doi.org/10.3390/v15091944

Ejemplares similares

Enhanced Th1/Th17 Functions of CD161(+) CD8(+) T Cells in Mucosal Tissues of Rhesus Macaques
por: Rout, Namita
Publicado: (2016)

Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques
por: Roberts, Emily R., et al.
Publicado: (2016)

The loss of CCR6+ and CD161+ CD4+ T cell homeostasis contributes to disease progression in SIV-infected rhesus macaques
por: McGary, Colleen S., et al.
Publicado: (2017)

Recombinant Simian Varicella Virus-Simian Immunodeficiency Virus Vaccine Induces T and B Cell Functions and Provides Partial Protection against Repeated Mucosal SIV Challenges in Rhesus Macaques
por: Pahar, Bapi, et al.
Publicado: (2022)

P16-47. Interleukin (IL)-21 induces cytolytic molecule perforin in CD4 and CD8 T cells without CD4 activation in chronically SIV infected rhesus macaques
por: Pahwa, S, et al.
Publicado: (2009)

Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8(+) T Cells Conveys the Ability to Suppress SIV Replication
por: Barsov, Eugene V., et al.
Publicado: (2011)

Distinct Expression Patterns of CD69 in Mucosal and Systemic Lymphoid Tissues in Primary SIV Infection of Rhesus Macaques
por: Wang, Xiaolei, et al.
Publicado: (2011)

Identification of Cytolytic CD161(−)CD56(+) Regulatory CD8 T Cells in Human Peripheral Blood
por: Hu, Dan, et al.
Publicado: (2013)

Rapid Loss of CD4 T Cells by Pyroptosis during Acute SIV Infection in Rhesus Macaques
por: He, Xuan, et al.
Publicado: (2022)

Correction: Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8(+) T Cells Conveys the Ability to Suppress SIV Replication
por: Barsov, Eugene V., et al.
Publicado: (2018)

In situ detection of Gag-specific CD8(+ )cells in the GI tract of SIV infected Rhesus macaques
por: Tjernlund, Annelie, et al.
Publicado: (2010)

Overexpression of CD6 and PD-1 Identifies Dysfunctional CD8(+) T-Cells During Chronic SIV Infection of Rhesus Macaques
por: Enyindah-Asonye, Gospel, et al.
Publicado: (2020)

MHC and KIR Polymorphisms in Rhesus Macaque SIV Infection
por: Walter, Lutz, et al.
Publicado: (2015)

Cytotoxic Capacity of SIV-Specific CD8(+) T Cells against Primary Autologous Targets Correlates with Immune Control in SIV-Infected Rhesus Macaques
por: Mendoza, Daniel, et al.
Publicado: (2013)

SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques
por: Hu, Haitao, et al.
Publicado: (2011)

Protection against SIV in Rhesus Macaques Using Albumin and CD4-Based Vector-Mediated Gene Transfer
por: Spitsin, Sergei, et al.
Publicado: (2020)

CD8(+) T cells control SIV infection using both cytolytic effects and non-cytolytic suppression of virus production
por: Policicchio, Benjamin B., et al.
Publicado: (2023)

Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques
por: Tolbert, William D., et al.
Publicado: (2022)

Biologically-Directed Modeling Reflects Cytolytic Clearance of SIV-Infected Cells In Vivo in Macaques
por: Wick, W. David, et al.
Publicado: (2012)

IL-2 immunotherapy in chronically SIV-infected Rhesus Macaques
por: Garibal, Julie, et al.
Publicado: (2012)

SIV Infection Facilitates Mycobacterium tuberculosis Infection of Rhesus Macaques
por: Guo, Ming, et al.
Publicado: (2017)

Rhesus macaque IFITM3 gene polymorphisms and SIV infection
por: Winkler, Michael, et al.
Publicado: (2017)

Assessment of anti-CD20 antibody pre-treatment for augmentation of CAR-T cell therapy in SIV-infected rhesus macaques
por: Pampusch, Mary S., et al.
Publicado: (2023)

Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection
por: Hao, Xing Pei, et al.
Publicado: (2015)

Impact of Early ARV Initiation on Relative Proportions of Effector and Regulatory CD8 T Cell in Mesenteric Lymph Nodes and Peripheral Blood During Acute SIV Infection of Rhesus Macaques
por: Yero, Alexis, et al.
Publicado: (2022)

Treatment with IL-7 Prevents the Decline of Circulating CD4(+) T Cells during the Acute Phase of SIV Infection in Rhesus Macaques
por: Vassena, Lia, et al.
Publicado: (2012)

Similar Impact of CD8+ T Cell Responses on Early Virus Dynamics during SIV Infections of Rhesus Macaques and Sooty Mangabeys
por: Kouyos, Roger D., et al.
Publicado: (2010)

Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques
por: Moukambi, Félicien, et al.
Publicado: (2015)

Mucosal T follicular helper cells in SIV-infected rhesus macaques: contributing role of IL-27
por: Moukambi, Félicien, et al.
Publicado: (2019)

Loss and regain of SIV control upon CD8+ cell depletion in vivo in SIV-controller macaques is not associated with efficient SIV specific CD8+ T-cells
por: Hamimi, C, et al.
Publicado: (2012)

Mid-titer human convalescent plasma administration results in suboptimal prophylaxis against SARS-CoV-2 infection in rhesus macaques
por: Beddingfield, Brandon J., et al.
Publicado: (2023)

Comparative Analysis of Immune Activation Markers of CD8(+) T Cells in Lymph Nodes of Different Origins in SIV-Infected Chinese Rhesus Macaques
por: Liu, Jinbiao, et al.
Publicado: (2016)

Development of an anti-CAR antibody response in SIV-infected rhesus macaques treated with CD4-MBL CAR/CXCR5 T cells
por: Davey, Brianna C., et al.
Publicado: (2022)

P11-19. Altered mucosal distribution of SIV-specific T cells in Rhesus macaques infected with the live-attenuated Rev-independent SIV
por: Valentin, A, et al.
Publicado: (2009)

Comparison of Influenza and SIV Specific CD8 T Cell Responses in Macaques
por: Jegaskanda, Sinthujan, et al.
Publicado: (2012)

Viral and immunological factors associated with breast milk transmission of SIV in rhesus macaques
por: Amedee, Angela M, et al.
Publicado: (2004)

Lipopolysaccharide Induces Immune Activation and SIV Replication in Rhesus Macaques of Chinese Origin
por: Bao, Rong, et al.
Publicado: (2014)

Correction: Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques
por: Moukambi, Félicien, et al.
Publicado: (2016)

Evaluation of Functional NK Cell Responses in Vaccinated and SIV-Infected Rhesus Macaques
por: Vargas-Inchaustegui, Diego A., et al.
Publicado: (2016)

Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV
por: Marshall, Vickie A., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qjhdqgrbitosof3i39gt44ohnl