Body Temperature Drop as a Humane Endpoint in Snake Venom-Lethality Neutralization Tests

Snake venom neutralization potency tests are required for quality control assessment by manufacturers and regulatory authorities. These assays require the use of large numbers of mice that manifest severe signs associated with pain and distress and long periods of suffering. Despite this, many anima...

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Detalles Bibliográficos
Autores principales: De Jesus, Rosa, Tratner, Adam E., Madrid, Alanna, Rivera-Mondragón, Andrés, Navas, Goy E., Lleonart, Ricardo, Britton, Gabrielle B., Fernández, Patricia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535418/
https://www.ncbi.nlm.nih.gov/pubmed/37755951
http://dx.doi.org/10.3390/toxins15090525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535418/
https://www.ncbi.nlm.nih.gov/pubmed/37755951
http://dx.doi.org/10.3390/toxins15090525

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