Cargando…
Body Temperature Drop as a Humane Endpoint in Snake Venom-Lethality Neutralization Tests
Snake venom neutralization potency tests are required for quality control assessment by manufacturers and regulatory authorities. These assays require the use of large numbers of mice that manifest severe signs associated with pain and distress and long periods of suffering. Despite this, many anima...
Autores principales: | De Jesus, Rosa, Tratner, Adam E., Madrid, Alanna, Rivera-Mondragón, Andrés, Navas, Goy E., Lleonart, Ricardo, Britton, Gabrielle B., Fernández, Patricia L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535418/ https://www.ncbi.nlm.nih.gov/pubmed/37755951 http://dx.doi.org/10.3390/toxins15090525 |
Ejemplares similares
-
In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom
por: Ledsgaard, Line, et al.
Publicado: (2022) -
Assessing a 6-h endpoint observation time in the lethality neutralization assay used to evaluate the preclinical efficacy of snake antivenoms
por: Durán, Gina, et al.
Publicado: (2021) -
Snakes, Snake Venoms, and Antivenenes
por: Ranck, E. M.
Publicado: (1902) -
Efficacy of Indian polyvalent snake antivenoms against Sri Lankan snake venoms: lethality studies or clinically focussed in vitro studies
por: Maduwage, Kalana, et al.
Publicado: (2016) -
Researches on Snake-Venom
por: Mitchell, S. Weir
Publicado: (1885)