The Disruption of a Nuclear Export Signal in the C-Terminus of the Herpes Simplex Virus 1 Determinant of Pathogenicity UL24 Protein Leads to a Syncytial Plaque Phenotype

UL24 of herpes simplex virus 1 (HSV-1) has been shown to be a determinant of pathogenesis in mouse models of infection. The N-terminus of UL24 localizes to the nucleus and drives the redistribution of nucleolin and B23. In contrast, when expressed alone, the C-terminal domain of UL24 accumulates in...

Descripción completa

Detalles Bibliográficos
Autores principales: Gonzalez, Carmen Elena, Ben Abdeljelil, Nawel, Pearson, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535440/
https://www.ncbi.nlm.nih.gov/pubmed/37766377
http://dx.doi.org/10.3390/v15091971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535440/
https://www.ncbi.nlm.nih.gov/pubmed/37766377
http://dx.doi.org/10.3390/v15091971

Ejemplares similares