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The Synergistic Influence of Polyflavonoids from Citrus aurantifolia on Diabetes Treatment and Their Modulation of the PI3K/AKT/FOXO1 Signaling Pathways: Molecular Docking Analyses and In Vivo Investigations

This study was aimed at probing the modulatory influence of polyflavonoids extracted from Citrus aurantifolia, lemon peel extract (LPE-polyflavonoids), on attenuating diabetes mellitus (DM) and its complications. HPLC investigations of the LPE exhibited the incidence of five flavonoids, including di...

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Detalles Bibliográficos
Autores principales: Hassan, Mohamed A., Elmageed, Ghada M. Abd, El-Qazaz, Ibtehal G., El-Sayed, Doaa S., El-Samad, Lamia M., Abdou, Heba M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535482/
https://www.ncbi.nlm.nih.gov/pubmed/37765275
http://dx.doi.org/10.3390/pharmaceutics15092306