A CRISPR Screen of HIV Dependency Factors Reveals That CCNT1 Is Non-Essential in T Cells but Required for HIV-1 Reactivation from Latency

We sought to explore the hypothesis that host factors required for HIV-1 replication also play a role in latency reversal. Using a CRISPR gene library of putative HIV dependency factors, we performed a screen to identify genes required for latency reactivation. We identified several HIV-1 dependency...

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Detalles Bibliográficos
Autores principales: Hafer, Terry L., Felton, Abby, Delgado, Yennifer, Srinivasan, Harini, Emerman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535513/
https://www.ncbi.nlm.nih.gov/pubmed/37766271
http://dx.doi.org/10.3390/v15091863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535513/
https://www.ncbi.nlm.nih.gov/pubmed/37766271
http://dx.doi.org/10.3390/v15091863

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