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A CRISPR Screen of HIV Dependency Factors Reveals That CCNT1 Is Non-Essential in T Cells but Required for HIV-1 Reactivation from Latency
We sought to explore the hypothesis that host factors required for HIV-1 replication also play a role in latency reversal. Using a CRISPR gene library of putative HIV dependency factors, we performed a screen to identify genes required for latency reactivation. We identified several HIV-1 dependency...
Autores principales: | Hafer, Terry L., Felton, Abby, Delgado, Yennifer, Srinivasan, Harini, Emerman, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535513/ https://www.ncbi.nlm.nih.gov/pubmed/37766271 http://dx.doi.org/10.3390/v15091863 |
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