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Algorithmically Reconstructed Molecular Pathways as the New Generation of Prognostic Molecular Biomarkers in Human Solid Cancers

Individual gene expression and molecular pathway activation profiles were shown to be effective biomarkers in many cancers. Here, we used the human interactome model to algorithmically build 7470 molecular pathways centered around individual gene products. We assessed their associations with tumor t...

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Detalles Bibliográficos
Autores principales: Zolotovskaia, Marianna, Kovalenko, Maks, Pugacheva, Polina, Tkachev, Victor, Simonov, Alexander, Sorokin, Maxim, Seryakov, Alexander, Garazha, Andrew, Gaifullin, Nurshat, Sekacheva, Marina, Zakharova, Galina, Buzdin, Anton A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535530/
https://www.ncbi.nlm.nih.gov/pubmed/37755705
http://dx.doi.org/10.3390/proteomes11030026