Imidazopyridine-Based Thiazole Derivatives as Potential Antidiabetic Agents: Synthesis, In Vitro Bioactivity, and In Silico Molecular Modeling Approach

A new series of thiazole derivatives (4a-p) incorporating imidazopyridine moiety was synthesized and assessed for their in vitro potential α-glucosidase potency using acarbose as a reference drug. The obtained results suggested that compounds 4a (docking score = −13.45), 4g (docking score = −12.87),...

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Detalles Bibliográficos
Autores principales: Hussain, Rafaqat, Rehman, Wajid, Khan, Shoaib, Maalik, Aneela, Hefnawy, Mohamed, Alanazi, Ashwag S., Khan, Yousaf, Rasheed, Liaqat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535535/
https://www.ncbi.nlm.nih.gov/pubmed/37765096
http://dx.doi.org/10.3390/ph16091288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535535/
https://www.ncbi.nlm.nih.gov/pubmed/37765096
http://dx.doi.org/10.3390/ph16091288

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