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Imidazopyridine-Based Thiazole Derivatives as Potential Antidiabetic Agents: Synthesis, In Vitro Bioactivity, and In Silico Molecular Modeling Approach
A new series of thiazole derivatives (4a-p) incorporating imidazopyridine moiety was synthesized and assessed for their in vitro potential α-glucosidase potency using acarbose as a reference drug. The obtained results suggested that compounds 4a (docking score = −13.45), 4g (docking score = −12.87),...
Autores principales: | Hussain, Rafaqat, Rehman, Wajid, Khan, Shoaib, Maalik, Aneela, Hefnawy, Mohamed, Alanazi, Ashwag S., Khan, Yousaf, Rasheed, Liaqat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535535/ https://www.ncbi.nlm.nih.gov/pubmed/37765096 http://dx.doi.org/10.3390/ph16091288 |
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