Stimulation of Hemolysis and Eryptosis by α-Mangostin through Rac1 GTPase and Oxidative Injury in Human Red Blood Cells

Background: Chemotherapy-related anemia is prevalent in up to 75% of patients, which may arise due to hemolysis and eryptosis. Alpha-mangostin (α-MG) is a polyphenolic xanthonoid found in the mangosteen tree (Garcinia mangostana) whose antitumor medicinal properties are well-established. Nevertheles...

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Detalles Bibliográficos
Autores principales: Alghareeb, Sumiah A., Alsughayyir, Jawaher, Alfhili, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535552/
https://www.ncbi.nlm.nih.gov/pubmed/37764276
http://dx.doi.org/10.3390/molecules28186495