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NMR-Verified Dearomatization of 5,7-Substituted Pyrazolo[1,5-a]pyrimidines

Tetrahydropyrazolo[1,5-a]pyrimidine (THPP) is an attractive scaffold for designing biologically active compounds. The most obvious way to obtain such compounds is to reduce pyrazolopyrimidines with complex hydrides, because the pyrimidine ring is reduced in the preference over the pyrazole ring. The...

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Detalles Bibliográficos
Autores principales: Novikova, Daria, Al Mustafa, Ammar, Grigoreva, Tatyana, Vorona, Svetlana, Selivanov, Stanislav, Tribulovich, Vyacheslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535613/
https://www.ncbi.nlm.nih.gov/pubmed/37764360
http://dx.doi.org/10.3390/molecules28186584