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Single-cell analysis of 5-aminolevulinic acid intraoperative labeling specificity for glioblastoma

OBJECTIVE: Glioblastoma (GBM) is the most common and aggressive malignant primary brain tumor, and resection is a key part of the standard of care. In fluorescence-guided surgery (FGS), fluorophores differentiate tumor tissue from surrounding normal brain. The heme synthesis pathway converts 5-amino...

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Detalles Bibliográficos
Autores principales: Liu, Zhouzerui, Mela, Angeliki, Argenziano, Michael G., Banu, Matei A., Furnari, Julia, Kotidis, Corina, Sperring, Colin P., Humala, Nelson, Mahajan, Aayushi, Bruce, Jeffrey N., Canoll, Peter, Sims, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535619/
https://www.ncbi.nlm.nih.gov/pubmed/37773782
http://dx.doi.org/10.3171/2023.7.JNS23122