Activation of STING by SAMHD1 Deficiency Promotes PANoptosis and Enhances Efficacy of PD-L1 Blockade in Diffuse Large B-cell Lymphoma

Genomic instability is a significant driver of cancer. As the sensor of cytosolic DNA, the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway plays a critical role in regulating anti-tumor immunity and cell death. However, the role and regulatory mechanisms of STING in dif...

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Detalles Bibliográficos
Autores principales: Cai, Yiqing, Chen, Xiaomin, Lu, Tiange, Fang, Xiaosheng, Ding, Mengfei, Yu, Zhuoya, Hu, Shunfeng, Liu, Jiarui, Zhou, Xiangxiang, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535696/
https://www.ncbi.nlm.nih.gov/pubmed/37781035
http://dx.doi.org/10.7150/ijbs.85236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535696/
https://www.ncbi.nlm.nih.gov/pubmed/37781035
http://dx.doi.org/10.7150/ijbs.85236

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