Pgam5-mediated PHB2 dephosphorylation contributes to endotoxemia-induced myocardial dysfunction by inhibiting mitophagy and the mitochondrial unfolded protein response

Numerous mitochondrial abnormalities are reported to result from excessive inflammation during endotoxemia. Prohibitin 2 (PHB2) and phosphoglycerate mutase 5 (Pgam5) have been associated with altered mitochondrial homeostasis in several cardiovascular diseases; however, their role in endotoxemia-rel...

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Detalles Bibliográficos
Autores principales: Cai, Chen, Li, Ziying, Zheng, Zemao, Guo, Zhongzhou, Li, Qian, Deng, Shuxian, Shi, Nengxian, Ou, Qing, Zhou, Hao, Guo, Zhigang, Chen, Zhongqing, Zhu, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535708/
https://www.ncbi.nlm.nih.gov/pubmed/37781037
http://dx.doi.org/10.7150/ijbs.85767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535708/
https://www.ncbi.nlm.nih.gov/pubmed/37781037
http://dx.doi.org/10.7150/ijbs.85767

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