Modified mRNA Formulation and Stability for Cardiac and Skeletal Muscle Delivery

Directly injecting naked or lipid nanoparticle (LNP)-encapsulated modified mRNA (modRNA) allows rapid and efficient protein expression. This non-viral technology has been used successfully in modRNA vaccines against SARS-CoV-2. The main challenges in using modRNA vaccines were the initial requiremen...

Descripción completa

Detalles Bibliográficos
Autores principales: Żak, Magdalena M., Kaur, Keerat, Yoo, Jimeen, Kurian, Ann Anu, Adjmi, Matthew, Mainkar, Gayatri, Yoon, Seonghun, Zangi, Lior
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535735/
https://www.ncbi.nlm.nih.gov/pubmed/37765147
http://dx.doi.org/10.3390/pharmaceutics15092176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535735/
https://www.ncbi.nlm.nih.gov/pubmed/37765147
http://dx.doi.org/10.3390/pharmaceutics15092176

Ejemplares similares