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Modified mRNA Formulation and Stability for Cardiac and Skeletal Muscle Delivery

Directly injecting naked or lipid nanoparticle (LNP)-encapsulated modified mRNA (modRNA) allows rapid and efficient protein expression. This non-viral technology has been used successfully in modRNA vaccines against SARS-CoV-2. The main challenges in using modRNA vaccines were the initial requiremen...

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Detalles Bibliográficos
Autores principales:	Żak, Magdalena M., Kaur, Keerat, Yoo, Jimeen, Kurian, Ann Anu, Adjmi, Matthew, Mainkar, Gayatri, Yoon, Seonghun, Zangi, Lior
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535735/ https://www.ncbi.nlm.nih.gov/pubmed/37765147 http://dx.doi.org/10.3390/pharmaceutics15092176

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