May 1,2-Dithiolane-4-carboxylic Acid and Its Derivatives Serve as a Specific Thioredoxin Reductase 1 Inhibitor?

Thioredoxin reductase is an essential enzyme that plays a crucial role in maintaining cellular redox homeostasis by catalyzing the reduction of thioredoxin, which is involved in several vital cellular processes. The overexpression of TrxR is often associated with cancer development. A series of 1,2-...

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Detalles Bibliográficos
Autores principales: Nikitjuka, Anna, Krims-Davis, Kristaps, Kaņepe-Lapsa, Iveta, Ozola, Melita, Žalubovskis, Raivis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535816/
https://www.ncbi.nlm.nih.gov/pubmed/37764424
http://dx.doi.org/10.3390/molecules28186647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535816/
https://www.ncbi.nlm.nih.gov/pubmed/37764424
http://dx.doi.org/10.3390/molecules28186647

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