Mycobacterium tuberculosis Central Metabolism Is Key Regulator of Macrophage Pyroptosis and Host Immunity

Metabolic dysregulation in Mycobacterium tuberculosis results in increased macrophage apoptosis or pyroptosis. However, mechanistic links between Mycobacterium virulence and bacterial metabolic plasticity remain ill defined. In this study, we screened random transposon insertions of M. bovis BCG to...

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Detalles Bibliográficos
Autores principales: Maxson, Michelle E., Das, Lahari, Goldberg, Michael F., Porcelli, Steven A., Chan, John, Jacobs, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535942/
https://www.ncbi.nlm.nih.gov/pubmed/37764917
http://dx.doi.org/10.3390/pathogens12091109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535942/
https://www.ncbi.nlm.nih.gov/pubmed/37764917
http://dx.doi.org/10.3390/pathogens12091109

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