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Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that plays an important role in gastrointestinal barrier function, tumorigenesis, and is an emerging drug target. The resident microbiota is capable of metabolizing tryptophan to metabolites that are AHR ligands (e.g., in...

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Detalles Bibliográficos
Autores principales: Patel, Dhwani, Murray, Iain A., Dong, Fangcong, Annalora, Andrew J., Gowda, Krishne, Coslo, Denise M., Krzeminski, Jacek, Koo, Imhoi, Hao, Fuhua, Amin, Shantu G., Marcus, Craig B., Patterson, Andrew D., Perdew, Gary H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535990/
https://www.ncbi.nlm.nih.gov/pubmed/37755265
http://dx.doi.org/10.3390/metabo13090985