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Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that plays an important role in gastrointestinal barrier function, tumorigenesis, and is an emerging drug target. The resident microbiota is capable of metabolizing tryptophan to metabolites that are AHR ligands (e.g., in...
Autores principales: | Patel, Dhwani, Murray, Iain A., Dong, Fangcong, Annalora, Andrew J., Gowda, Krishne, Coslo, Denise M., Krzeminski, Jacek, Koo, Imhoi, Hao, Fuhua, Amin, Shantu G., Marcus, Craig B., Patterson, Andrew D., Perdew, Gary H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535990/ https://www.ncbi.nlm.nih.gov/pubmed/37755265 http://dx.doi.org/10.3390/metabo13090985 |
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