Design and Synthesis of Novel Thieno[3,2-c]quinoline Compounds with Antiproliferative Activity on RET-Dependent Medullary Thyroid Cancer Cells

[Image: see text] RET kinase gain-of-function mutations represent the main cause of the high aggressiveness and invasiveness of medullary thyroid cancer (MTC). The selective inhibition of the RET kinase is a suitable strategy for the treatment of this endocrine neoplasia. Herein, we performed an inn...

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Detalles Bibliográficos
Autores principales: La Monica, Gabriele, Pizzolanti, Giuseppe, Baiamonte, Concetta, Bono, Alessia, Alamia, Federica, Mingoia, Francesco, Lauria, Antonino, Martorana, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536062/
https://www.ncbi.nlm.nih.gov/pubmed/37779971
http://dx.doi.org/10.1021/acsomega.3c03578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536062/
https://www.ncbi.nlm.nih.gov/pubmed/37779971
http://dx.doi.org/10.1021/acsomega.3c03578

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