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An In Silico Design of Peptides Targeting the S1/S2 Cleavage Site of the SARS-CoV-2 Spike Protein

SARS-CoV-2, responsible for the COVID-19 pandemic, invades host cells via its spike protein, which includes critical binding regions, such as the receptor-binding domain (RBD), the S1/S2 cleavage site, the S2 cleavage site, and heptad-repeat (HR) sections. Peptides targeting the RBD and HR1 inhibit...

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Detalles Bibliográficos
Autores principales: Ho, Chian, Nazarie, Wan Fahmi Wan Mohamad, Lee, Ping-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536081/
https://www.ncbi.nlm.nih.gov/pubmed/37766336
http://dx.doi.org/10.3390/v15091930