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Neuroprotective Properties of Oleanolic Acid—Computational-Driven Molecular Research Combined with In Vitro and In Vivo Experiments

Oleanolic acid (OA), as a ubiquitous compound in the plant kingdom, is studied for both its neuroprotective and neurotoxic properties. The mechanism of acetylcholinesterase (AChE) inhibitory potential of OA is investigated using molecular dynamic simulations (MD) and docking as well as biomimetic te...

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Detalles Bibliográficos
Autores principales: Stępnik, Katarzyna, Kukula-Koch, Wirginia, Plazinski, Wojciech, Rybicka, Magda, Gawel, Kinga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536188/
https://www.ncbi.nlm.nih.gov/pubmed/37765042
http://dx.doi.org/10.3390/ph16091234