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Neuroprotective Properties of Oleanolic Acid—Computational-Driven Molecular Research Combined with In Vitro and In Vivo Experiments
Oleanolic acid (OA), as a ubiquitous compound in the plant kingdom, is studied for both its neuroprotective and neurotoxic properties. The mechanism of acetylcholinesterase (AChE) inhibitory potential of OA is investigated using molecular dynamic simulations (MD) and docking as well as biomimetic te...
Autores principales: | Stępnik, Katarzyna, Kukula-Koch, Wirginia, Plazinski, Wojciech, Rybicka, Magda, Gawel, Kinga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536188/ https://www.ncbi.nlm.nih.gov/pubmed/37765042 http://dx.doi.org/10.3390/ph16091234 |
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