Effect of Repeated Administration of ɣ-Valerolactone (GVL) and GHB in the Mouse: Neuroadaptive Changes of the GHB and GABAergic System

Background: Gamma-hydroxybutyric acid (GHB) at low dosages has anxiolytic effects and promotes REM sleep and low-wave deep sleep. In the U.S., the legal form of GHB is prescribed to adults suffering from narcolepsy-associated cataplexy; the sodium salt of GHB is reserved for alcohol-addiction treatm...

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Detalles Bibliográficos
Autores principales: Frisoni, Paolo, Corli, Giorgia, Bilel, Sabrine, Tirri, Micaela, Gasparini, Laura Camilla, Alfieri, Letizia, Neri, Margherita, De-Giorgio, Fabio, Marti, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536195/
https://www.ncbi.nlm.nih.gov/pubmed/37765033
http://dx.doi.org/10.3390/ph16091225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536195/
https://www.ncbi.nlm.nih.gov/pubmed/37765033
http://dx.doi.org/10.3390/ph16091225

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