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Effect of Repeated Administration of ɣ-Valerolactone (GVL) and GHB in the Mouse: Neuroadaptive Changes of the GHB and GABAergic System
Background: Gamma-hydroxybutyric acid (GHB) at low dosages has anxiolytic effects and promotes REM sleep and low-wave deep sleep. In the U.S., the legal form of GHB is prescribed to adults suffering from narcolepsy-associated cataplexy; the sodium salt of GHB is reserved for alcohol-addiction treatm...
Autores principales: | Frisoni, Paolo, Corli, Giorgia, Bilel, Sabrine, Tirri, Micaela, Gasparini, Laura Camilla, Alfieri, Letizia, Neri, Margherita, De-Giorgio, Fabio, Marti, Matteo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536195/ https://www.ncbi.nlm.nih.gov/pubmed/37765033 http://dx.doi.org/10.3390/ph16091225 |
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