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AURKA inhibitor-induced PD-L1 upregulation impairs antitumor immune responses

INTRODUCTION: Tumor immunotherapy targeting PD-L1 has emerged as one of the powerful tools for tumor therapy. Numerous studies indicate that tumor-targeted drugs critically have an influence on the interaction between the immune system and tumors by changing the expression of PD-L1, which is benefic...

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Detalles Bibliográficos
Autores principales: Meng, Bi, Zhao, Xuan, Jiang, Shuchang, Xu, Zijian, Li, Sijin, Wang, Xu, Ma, Wen, Li, Liantao, Liu, Dan, Zheng, Junnian, Peng, Hui, Shi, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536236/
https://www.ncbi.nlm.nih.gov/pubmed/37781397
http://dx.doi.org/10.3389/fimmu.2023.1182601