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The Path from Nasal Tissue to Nasal Mucosa on Chip: Part 1—Establishing a Nasal In Vitro Model for Drug Delivery Testing Based on a Novel Cell Line

In recent years, there has been a significant increase in the registration of drugs for nasal application with systemic effects. Previous preclinical in vitro test systems for transmucosal drug absorption studies have mostly been based on primary cells or on tumor cell lines such as RPMI 2650, but b...

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Detalles Bibliográficos
Autores principales: Bendas, Sebastian, Koch, Eugen Viktor, Nehlsen, Kristina, May, Tobias, Dietzel, Andreas, Reichl, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536430/
https://www.ncbi.nlm.nih.gov/pubmed/37765214
http://dx.doi.org/10.3390/pharmaceutics15092245