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ALDH1A Inhibition Suppresses Colitis and Alters α4β7 Integrin Expression on Activated T Cells in Mdr1a(−/−) Mice

There are limited pharmacological treatment options for inflammatory bowel disease (IBD), and some of these options are expensive and administered by injection or infusion. Thus, new cheaper and easier (oral) treatment options are needed. ALDH1A enzymes produce retinoic acid that can affect intestin...

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Detalles Bibliográficos
Autores principales: Seamons, Audrey, Staucean, Olesya, Snyder, Jessica M., Brabb, Thea, Hsu, Charlie C., Paik, Jisun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536456/
https://www.ncbi.nlm.nih.gov/pubmed/37764666
http://dx.doi.org/10.3390/nu15183883