Improved Pharmacokinetic Feasibilities of Mirabegron-1,2-Ethanedisulfonic Acid, Mirabegron-1,5-Naphthalenedisulfonic Acid, and Mirabegron-L-Pyroglutamic Acid as Co-Amorphous Dispersions in Rats and Mice

Mirabegron (MBR) is a β(3)-adrenoceptor agonist used for treating overactive bladder syndrome. Due to its poor solubility and low bioavailability (F), the development of novel MBR formulations has garnered increasing attention. Recently, co-amorphous dispersions of MBR, such as MBR-1,2-ethanedisulfo...

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Detalles Bibliográficos
Autores principales: Kim, Seo-Yeon, You, Byung Hoon, Bae, Mingoo, Han, Seung Yon, Jung, Kiwon, Choi, Young Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536516/
https://www.ncbi.nlm.nih.gov/pubmed/37765246
http://dx.doi.org/10.3390/pharmaceutics15092277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536516/
https://www.ncbi.nlm.nih.gov/pubmed/37765246
http://dx.doi.org/10.3390/pharmaceutics15092277

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