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One-Step Assembly of a PRRSV Infectious cDNA Clone and a Convenient CRISPR/Cas9-Based Gene-Editing Technology for Manipulation of PRRSV Genome

Porcine reproductive and respiratory syndrome (PRRS) has been a persistent challenge for the swine industry for over three decades due to the lack of effective treatments and vaccines. Reverse genetics systems have been extensively employed to build rapid drug screening platforms and develop genetic...

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Detalles Bibliográficos
Autores principales: Zhang, Hejin, Duan, Kaiqi, Du, Yingbin, Xiao, Shaobo, Fang, Liurong, Zhou, Yanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536534/
https://www.ncbi.nlm.nih.gov/pubmed/37766223
http://dx.doi.org/10.3390/v15091816