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Investigation of the Effect on the Albumin Binding Moiety for the Pharmacokinetic Properties of (68)Ga-, (205/206)Bi-, and (177)Lu-Labeled NAPamide-Based Radiopharmaceuticals

Although radiolabeled alpha-melanocyte stimulating hormone-analogue NAPamide derivatives are valuable melanoma-specific diagnostic probes, their rapid elimination kinetics and high renal uptake may preclude them from being used in clinical settings. We aimed at improving the pharmacokinetics of radi...

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Detalles Bibliográficos
Autores principales: Szücs, Dániel, Szabó, Judit P., Arató, Viktória, Gyuricza, Barbara, Szikra, Dezső, Tóth, Imre, Képes, Zita, Trencsényi, György, Fekete, Anikó
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536547/
https://www.ncbi.nlm.nih.gov/pubmed/37765089
http://dx.doi.org/10.3390/ph16091280