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Negr1-Derived Peptides Trigger ALK Degradation and Halt Neuroblastoma Progression In Vitro and In Vivo

Neuroblastoma is among the most common childhood cancers. Neuroblastoma in advanced stages is one of the most intractable pediatric cancers, notwithstanding the recent therapeutic advances. ALK mutations are among the leading cause of hereditary neuroblastoma and account for more than 14% of the som...

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Detalles Bibliográficos
Autores principales: Pischedda, Francesca, Ghirelli, Alessia, Tripathi, Vasvi, Piccoli, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536585/
https://www.ncbi.nlm.nih.gov/pubmed/37765276
http://dx.doi.org/10.3390/pharmaceutics15092307