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Characterization and In Vivo Antiangiogenic Activity Evaluation of Morin-Based Cyclodextrin Inclusion Complexes

Morin (MRN) is a natural compound with antiangiogenic, antioxidant, anti-inflammatory, and anticancer activity. However, it shows a very low water solubility (28 μg/mL) that reduces its oral absorption, making bioavailability low and unpredictable. To improve MRN solubility and positively affect its...

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Detalles Bibliográficos
Autores principales: De Gaetano, Federica, Margani, Fatima, Barbera, Vincenzina, D’Angelo, Valeria, Germanò, Maria Paola, Pistarà, Venerando, Ventura, Cinzia Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536596/
https://www.ncbi.nlm.nih.gov/pubmed/37765179
http://dx.doi.org/10.3390/pharmaceutics15092209