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Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis

BACKGROUND: Gastric cancer (GC) is a fatal cancer with unclear pathogenesis. In this study, we explored the function and potential mechanisms of intercellular adhesion molecule 2 (ICAM2) in the development and advancement of GC. METHODS: Quantitative real-time polymerase chain reaction (qRT-PCR) and...

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Detalles Bibliográficos
Autores principales: Tang, Xiaocheng, Huang, Jintuan, Jiang, Yingming, Qiu, Jun, Li, Tuoyang, Li, Weiyao, Chen, Zijian, Huang, Zhenze, Yu, Xihu, Yang, Tao, Ji, Xiang, Tan, Rongchang, lv, Li, Yang, Zuli, Chen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536727/
https://www.ncbi.nlm.nih.gov/pubmed/37759298
http://dx.doi.org/10.1186/s12967-023-04536-2