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Elucidating the Role of a Calcium-Binding Loop in an x-Prolyl Aminodipeptidase from Lb. helveticus

[Image: see text] Prolyl aminodipeptidase (PepX) is an α/β hydrolase that cleaves at penultimate N-terminal prolyl peptide bonds. The crystal structure of PepX from Lactobacillus helveticus exhibits a calcium-binding loop within the catalytic domain. The calcium-binding sequence of xDxDxDGxxD within...

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Detalles Bibliográficos
Autores principales: Ryder, Stephanie, Pedigo, Jacob, Ojennus, Deanna Dahlke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10536834/
https://www.ncbi.nlm.nih.gov/pubmed/37779945
http://dx.doi.org/10.1021/acsomega.3c05639